BDBM50072026 CHEMBL3407851

SMILES CNc1ncc2ccc(Oc3cc(ccc3Cl)C(=O)c3c(-c4ccccc4)n(C)n(-c4ccccc4)c3=O)cc2n1

InChI Key InChIKey=LTKYUQAQPQMHNJ-UHFFFAOYSA-N

Data  6 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50072026   

TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50072026(CHEMBL3407851)
Affinity DataIC50:  13nMAssay Description:Inhibition of recombinant BRAF V600E kinase domain mutant (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed